这个等位基因是Fgf8tm1.1Mrt衍生而来的,带有这种基因的小鼠与β-actin Flp小鼠杂交后产生了杂合子后代,这些后代拥有一个经过重组的Fgf8基因,去除了诺卡因抗性基因座,且2号和3号外显子仍被loxP序列环绕。(来源:J:45909)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd-Hprt1b-m3
Targeted
插入
--
1
11
47

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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