在内源性起始密码子后插入了一个cre基因,并在cre基因之后插入了一个frt-flanked诺卡因选择子。在将这个cre基因和选择子通过flp介导的重组从胚胎干细胞中去除后,这个启动子在出生后在皮肤、毛囊、眼睛、口腔和食管中都保持活性。(来源:J:69463)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
12
16

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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