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中文
将lacZ基因和诺卡因抗性基因座插入了第2外显子，紧接在起始密码子之前。第2外显子的三分之二以及部分内含子2被删除。这个等位基因在内源性启动子的调控下表达β-半乳糖苷酶。北半球分析显示，纯合子小鼠并未产生野生型mRNA。对胸腺、肺和脑的免疫组化检查在纯合子小鼠中未检测到野生型蛋白质。(来源：J:36890, J:51408)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
