一种新霉素抗性基因座替换了大约1kb的基因组序列,包括3号外显子和3号内含子的部分。 Western blot分析在纯合突变小鼠的肌肉中未检测到该蛋白质。(来源:J:28777)
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A neomycin resistance cassette replaced approximately 1kb of genomic sequence including part of exon 3 and intron 3. Western blot analysis did not detect the protein in muscle of homozygous mutant mice. (J:28777)