将启动子区域和第一个外显子替换为诺卡因抗性基因 cassette,对同源突变小鼠神经组织和其它外围组织产生的样本进行 Western blot 分析并未检测到任何蛋白质。(来源:J:45851)
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Replacement of the promoter region and first exon with a neomycin cassette. Western blot analysis on samples derived from nervous tissue and other peripheral tissues of homozygous mutant mice failed to detect any protein. (J:45851)