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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Gdnf
tm1Bbd
Alias:
GDNF/lacZ
Gdnf
LacZ
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基础信息
表型特征
文献报道
在第一个编码外显子中插入了lacZ基因,并在lacZ基因后面插入了抗氨苄青霉素的质粒。这个等位基因表达出一种融合蛋白,由GDNF的前8个氨基酸和β-半乳糖苷酶组成。(来源:J:33809)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2136844
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
插入
--
1
3
12
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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