将新霉素抗性基因 cassette 插入第6外显子,该外显子编码IgII区域。通过对肝脏中转基因杂合子动物的Northern blot检测,未发现mRNA。免疫组织化学分析在转基因纯合子小鼠的肺部也未检测到蛋白质。(来源:J:50677)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
插入
--
1
--
29

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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