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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Fgfr3
tm5.1Cxd
Alias:
Fgfr3
365
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基础信息
表型特征
文献报道
在Fgfr3tm5Cxd这个衍生品中,引入了一个点突变,将365位的密码子从丝氨酸(Ser)变为 cysteine (Cys),这个变化用S365C表示。同时,相邻的loxP引导的诺卡因替换单位通过Cre介导的重组被去除了(来源:J:67780)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2135677
129S6/SvEvTac
Targeted
Insertion, Single point
--
1
39
1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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