Egfr^tm1Wag

Part of the first exon was replaced by an in frame lacZ gene, followed by either a neomycin or a hygromycin selection cassette. These two different constructs were used to generate separate lines of mice, but the analysis did not distinguish between them. An EGFR-beta-galactosidase fusion protein was produced from this allele that was expressed under the control of the endogenous gene promoter. (J:26834)