一种新霉素抗性基因替换了exon 2的一部分,包括剪接接受体位点和大部分编码序列。在纯合胚胎中检测不到这个等位基因产生的转录本(数据未显示),并且对纯合胚胎的免疫组化实验也证实了未检测到任何可编码蛋白的存在。(来源:J:40601)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入,基因内删除
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1
3
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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