在小鼠中,一个新霉素抗性基因座替换了编码第一跨膜域和一个保守丝氨酸的4kb序列,但Northern印迹分析在巨噬细胞、肾上腺、卵巢和睾丸中并未检测到任何转录本。同源突变小鼠的巨噬细胞、肾上腺、卵巢和睾丸的Western印迹实验也未发现该蛋白质。(来源:J:63468)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd
Targeted
插入,基因内删除
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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