这个基因组片段,包含了编码蛋白质末端羧基部分的序列,被替换了 neo 氨基甲烷抗性基因座。北标显示,纯合小鼠中这个等位基因并未检测到完整转录本。在这些小鼠的组织中,DGAT 活性要么缺失要么显著降低。(来源:J:61885)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
插入,基因内删除
--
1
2
33

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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