一种新霉素抗性基因座替换了包含该基因完整编码序列的基因组片段。 Western blot分析证实了来自纯合小鼠的巨噬细胞裂解物中没有CD14蛋白(来源:J:65107)
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A neomycin resistance cassette replaced a genomic fragment containing the entire coding sequences of the gene. Western blot analysis confirmed an absence of CD14 protein in macrophage lysates derived from homozygous mice. (J:65107)