在翻译起始密码子后直接连接了一个无启动子的lacZ基因,后面跟着一个诺卡因选择标记。对E13.5同源胚胎提取的RNA进行Northern blot分析显示,野生型转录本无法检测到。对同源小鼠胸腺、脾和淋巴结中细胞的流式细胞术分析也证实,细胞表面没有稳定编码蛋白表达。(来源:J:68069)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
--
90

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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