将新霉素抗性基因 cassette 插入基因的起始编码 exon 中。在新生纯合突变小鼠大脑的提取物 Western blot 中未检测到蛋白质。(来源:J:45083)
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Insertion of a neomycin cassette into the first coding exon of the gene. No protein was detectable in Western blots of lysates from newborn homozygous mutant mouse brains. (J:45083)