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中文
在exon 4插入了一点突变，将阿尔法474的Alanine替换为Threonine（p.A474T）。通过Cre介导的重组，去除了内含子3中的loxP标记的Neomycin抗性基因元件。这种突变导致GRE介导的转录激活异常，并阻止了二聚体形成。（来源：J:67720, J:121199）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
