在一段外显子下游放置了一个loxP位点,然后将一个含诺卡因-胸腺嘧啶激酶表达元件的敲除柄插入上游内含子中。通过注射的Cre质粒的暂时表达,移除了诺卡因-胸腺嘧啶元件,但保留了敲除的外显子,从而在产生转基因小鼠前,实现了元件的剔除。(来源:J:119128)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部