从起始密码子到基本 helix-loop-helix (bHLH) 区域,通过部分第一个内含子,替换这些序列为PGK-neomycin cassette。通过Northern blot分析,同源突变体中未检测到功能性的mRNA。(来源:J:37117)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count