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中文
点突变是通过同源重组引入的，它改变了对应于密码子483的序列，从赖氨酸变为谷氨酰胺。通过暂时的Cre重组酶表达，去除了第十号内含子中的loxP介导的诺卡因/胸腺嘧啶激酶元件，留下一个loxP位点。(来源：J:62289)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
