在第1内含子的两个位置,从exons 2到7,各有一个单个的loxP位点。构建中包含了一个在下游loxP位点之后引入的无启动子的lacZ报告基因,通过lacZ的表达来检测cre介导的重组。北标分析显示,删除等位基因的表达不受loxP位点的影响。(来源:J:78985)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
--
69

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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