在exon 2内插入并整合了一个lacZ基因,接着是一个诺卡因选择标记。 Western blot结果显示,这种等位基因的野生型转录本表达被消除。然而,β-半乳糖苷酶融合蛋白在内源性启动子的调控下被表达。(来源:J:50964)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd
Targeted
插入
--
1
4
19

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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