在第一个编码外显子(Exon 2)插入了诺美西林(cassette)。对成年纯合小鼠肝微粒体进行的 Western blot 分析显示,这个等位基因编码的蛋白质无法检测到。(来源:J:25724)
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A neomycin cassette was inserted into exon 2, which is the first coding exon. Western blot analysis on liver microsomes derived from adult homozygous mice demonstrated that no detectable protein was encoded by this allele. (J:25724)