在exon 1中插入了新霉素选择座。对来自纯合小鼠肝脏的RNA进行Northern blot和RT-PCR分析后,未检测到来自这一等位基因的转录本。对来自纯合小鼠大脑组织提取物进行的Western blot分析也证实未检测到可识别的编码蛋白。(来源:J:50587)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count