在exon 1中插入了新霉素选择座。对来自纯合小鼠肝脏的RNA进行Northern blot和RT-PCR分析后,未检测到来自这一等位基因的转录本。对来自纯合小鼠大脑组织提取物进行的Western blot分析也证实未检测到可识别的编码蛋白。(来源:J:50587)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
9
22

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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