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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Was
tm1Sbs
Alias:
wasp-
Was
-
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基础信息
表型特征
文献报道
在exon 7中插入了新霉素 cassette,该exon编码GTPase结合区的一部分。通过Northern blot和Western blot分析,我们确认了雄性单体突变鼠中目标等位基因未产生转录物和蛋白质。(来源:J:48836)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
1861707
129S6/SvEvTac
Targeted
插入
--
1
5
83
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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