Log In|Sign Up
中文
这种等位基因被称为隐性突变，其特征是目标向量的特定位置插入，而非同源重组。构建中断了exon 3，插入了诺卡因筛选 cassette，带有thymidine kinase基因和载体序列位于内源exon 3的5'端。RT-PCR结果显示，这种等位基因产生了正常转录本的减少量，同时存在突变转录本，且在纯合小鼠血清中检测到了微量的蛋白质。(来源：J:37969)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
