雄性C3H/HeH小鼠接受了(3+3) Gy的分次X射线照射。有丝分裂中的G染色体研究显示,这种突变与一个从15D2到15F的倒位相关,该倒位位于一个区域,Trps1基因距离这个倒位的近端 breakpoint约0.8Mb。Trps1的表达显著降低,而倒位 breakpoints附近的其他候选基因表达不受影响。(参考文献:J:103253, J:121991, J:141036, J:155838)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C3H/HeH
Radiation induced
倒位
显性
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4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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