A neomycin cassette was used to replace the exons 2, 3, and a portion of 4. The affected exons code for the cysteine-rich domains I and II that are essential for binding of the ligand. (J:14424, J:92470)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count