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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Grm1
tm1Crpl
Alias:
mGlu1-
mGluR1
-
mGluR1
lacz
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基础信息
表型特征
文献报道
lacZ基因的诺美西林抗性 cassette 破坏了编码七跨膜螺旋域的外显子。对杂合突变小鼠大脑膜样物质的免疫印迹分析显示,使用针对蛋白质C端和N端部分的抗体检测时,未检测到任何原生蛋白。(来源:J:21644)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
1857986
129P2/OlaHsd-Hprt1b-m3
Targeted
插入
--
1
4
23
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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