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中文
Psen1基因的Exon3，编码起始密码子的部分，被删除并替换为诺卡因载体。同纯合突变小鼠大脑组织的Northern印迹显示，有少量的突变Psen1 mRNA，大小比野生型Psen1要小。同位素免疫沉淀- Western印迹在纯合突变小鼠中未检测到C端蛋白质片段。作者认为这种突变是一种无功能等位基因。(来源：J:40365)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
