一种由loxP位点 flank 的新霉素抗性基因座替换了位于Hoxd12和Hoxd13基因间区的调节元件RXI。通过与携带这种突变的Cre敲除小鼠杂交,这个选择性基因座被剔除了。(来源:J:47900)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S2/SvPas
Targeted
基因间区删除
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--
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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