基因组序列中,编码DNA结合区的部分在第3和4外显子被诺卡因载体替换。对纯合小鼠多种组织的总RNA进行RT-PCR分析显示,第2外显子和5-9的所有外显子在纯合个体中以低水平存在。作者并未排除在纯合子中可能产生少量突变蛋白的可能性。(来源:J:30560)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
插入,基因内删除
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1
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13

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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