在homeobox域的上游插入了lacZ/PGK-Hygro cassette,使得lacZ编码序列保持在内源框中。这个等位基因预计会表达Prrx2蛋白的前88个氨基酸,与Prrx2基因的表达模式相同,但连接的是β-半乳糖蛋白。由于去除了homeodomain和aristaless域,推测该蛋白质不会保留任何内源性生物化学活性。(来源:J:50488)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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