在编码成熟肽的exon 2中插入了一种新霉素抗性基因。对纯合胚胎提取的RNA进行RT-PCR分析后,未检测到来自这个等位基因的转录本。同源性酶免疫测定证实,纯合小鼠肺组织中未检测到活性肽。(来源:J:17694)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129X1/SvJ
Targeted
插入
--
1
3
30

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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