一段包含exon 1部分,包括起始翻译位点的0.5kb基因组片段被替换成诺卡因选择标记。对E12.5同源胚胎提取的RNA进行Northern blot分析显示,这个等位基因没有检测到转录本产生。对同源小鼠脊髓切片的免疫组化实验也证实,未检测到任何可识别的蛋白质。(来源:J:23773)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
插入,基因内删除
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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