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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Egr2
tm1Pch
Alias:
Krox20-lacZ
Krox20
lacZ
Krox20
-
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基础信息
表型特征
文献报道
在框内插入lacZ基因和一个诺卡因 cassette。这个等位基因表达出一个含有128个N端氨基酸和整个β-半乳糖苷酶蛋白的融合蛋白。这个融合物不包含锌指域,因此不具备DNA结合活性。(来源:J:16077)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
1857507
129S2/SvPas
Targeted
插入
--
1
5
31
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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