这个等位基因中,Cd1d1基因和它附近的Cd1d2基因都发生了突变。Cd1d1基因的编码序列被替换了新霉素选择标记 cassette,而Cd1d2基因的编码序列被删除了,但间隔序列保留了下来。通过对纯合小鼠胸腺细胞的流式细胞术分析,结果显示细胞表面没有稳定编码蛋白表达。(来源:J:47769)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S2/SvPas
Targeted
Insertion, Intergenic deletion
--
--
--
121

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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