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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Cd1
tm1Gru
Alias:
Cd1d
-
CD1tm1Gru
CD1d KO
Cd1d1/Cd1d2
tm1Gru
CD1
-
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基础信息
表型特征
文献报道
这个等位基因中,Cd1d1基因和它附近的Cd1d2基因都发生了突变。Cd1d1基因的编码序列被替换了新霉素选择标记 cassette,而Cd1d2基因的编码序列被删除了,但间隔序列保留了下来。通过对纯合小鼠胸腺细胞的流式细胞术分析,结果显示细胞表面没有稳定编码蛋白表达。(来源:J:47769)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
1857482
129S2/SvPas
Targeted
Insertion, Intergenic deletion
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--
--
121
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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