编码前导肽区域的序列被替换了新霉素抗性基因座。RT-PCR结果显示,来自纯合小鼠整个大脑RNA中该转录本缺失。免疫组化分析显示,纯合小鼠大脑杏仁核和大脑皮层的切片中未检测到该蛋白。(来源:J:17994, J:23082, J:47705)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count