一个新霉素插件替换了基因的启动子和前两个外显子。在纯合小鼠的脑组织 Western 印迹中未检测到编码蛋白。(来源:J:64297)
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A neomycin cassette replaced the promoter and the first two exons of the gene. Western blots of brain extracts did not detect any encoded protein in homozygous mice. (J:64297)