在exon 3插入了新霉素选择座。用来自纯合小鼠的RNA进行RT-PCR分析显示,这个等位基因产生了异常转录本。然而,对来自纯合小鼠激活脾细胞的免疫细胞化学实验并未检测到这个等位基因产生可检测到的蛋白质。(来源:J:17986, J:96542)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
插入
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1
8
354

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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