该基因通过诺卡因抗性载体进行了打靶突变,载体替换了编码最后两个外显子的序列。通过杂交 histochemistry 和免疫细胞化学,我们证明了纯合突变动物中没有转录物和蛋白质的存在。(来源:J:36926)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S/SvEv-Gpi1c
Targeted
插入,基因内删除
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1
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34

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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