这种突变最初是在通过使用In(X)1H反转染色体重组来抑制X染色体重组的实验中,在接受X射线处理的雄性小鼠女儿的半合子后代中被识别出来的,表现为致死性新生儿特征。后来发现,它与一个新的反转染色体In(X)3H相关联,其可能的断裂点位于A2和F1带,这种表型并不与反转染色体分离。(来源:J:16315, J:184888)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C3H/HeH x 101/H)F1
Radiation induced
未定义
隐性
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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