性染色体相关颤抖鼠的突变是一种X染色体倒位,其中一个 breakpoints 位置靠近 Pou3f4 基因。这种倒位选择性地去除了发育中内耳的 Pou3f4 基因表达,但不影响神经管。该突变也被证明与 Pou3f4tm1Cren 是等位的(来源:J:59387)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C3H/HeH x 101/H)F1
Radiation induced
倒位
半显性
1
4
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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