Mip^Hfi

A 76 bp deletion that removes 17 bp from the 3' end of exon 2 and 59 bp of intron 2. In the encoded mRNA, 165 bp of coding sequence is removed resulting from exon 2 being skipped during the splicing process. By immunoblot analysis on lens cell memebrane preparations, a smaller mutant protein was detected in homozygous mutant mice, although at lower levels that the wild-type protein. (J:70225)