在编码 mRNA 中,第 89 位的 T 被删除后,开放阅读框发生了变化。突变序列产生了长度为 125 个氨基酸的新型肽,这在对突变小鼠眼提取物进行 Western blotting 检测时得到了确认(来源:J:66541)
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A deletion of a T at position 89 in the encoded mRNA leads to a change in the open reading frame. The mutated sequence encodes a novel peptide of 125 amino acids, as detected in Western blotting of lens extracts derived from mutant mice. (J:66541)