补作试验表明,这种突变是原始棕色(Tyrp1b)突变的等位基因。Tyrp1b-c突变在(DBA/1 X C57BL/10)F1后代中被发现。由于DBA是Tyrp1b的纯合子,所以突变发生在C57BL/10背景上。
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Complementation testing demonstrated that this mutation is an allele of the original brown (Tyrp1b) mutation. The Tyrp1b-c allele was found among (DBA/1 X C57BL/10)F1 offspring. Because DBA is homozygous for Tyrp1b, the mutation occurred on C57BL10.