小鼠

Kdm1a - lysine (K)-specific demethylase 1A

Alias:
Aof2
Kdm1
Lsd1
mKIAA0601
D4Ertd478e
1810043O07Rik
Favorite
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括:DNA结合转录因子结合活性;组蛋白H3-di/monomethyl-lysine-4 FAD依赖性去甲基化活性;以及启动子特异性的染色质结合活性。参与多种过程,包括大分子代谢过程的负调控;细胞群增殖的正调控;以及髓细胞分化的调控。在组蛋白H3-K4去甲基化的上游或内部发挥作用;神经系统发育;以及RNA聚合酶II正向调控转录。位于染色质和细胞核中。在几个结构中表达,包括大脑;内细胞团;生殖系统;视网膜;和泌尿系统。与人类的KDM1A(赖氨酸去甲基化酶1A)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
4
20
52284 bp
92.85
18
12

Kdm1a Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Sequence
Comparison
Al agent
Tutorials
Back to top