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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
MVP - Major Vault Protein
Alias:
LRP
VAULT1
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Description
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码核膜复合体的主要成分。核膜是多亚基核糖核酸蛋白结构,可能参与核质运输。编码的蛋白质可能在多个细胞过程中发挥作用,通过调节MAP激酶、JAK/STAT和磷酸肌醇3-激酶/Akt信号通路。编码的蛋白质还在多药抗性中发挥作用,这个基因的表达可能是几种癌症的预后标志。已经观察到了这个基因的可变剪接转录变异。[RefSeq提供,2012年5月]
Related ID:
NCBI:9961
ENSEMBL:ENSG00000013364
HGNC:7531
UNIPROT:Q14764
OMIM:605088
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
9961
4
15
27646 bp
99.33
48
--
5
22
MVP Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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