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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
ARNT2 - Aryl Hydrocarbon Receptor Nuclear Translocator 2
Alias:
WEDAS
bHLHe1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个基本的-螺旋-环-螺旋-Per-Arnt-Sim(bHLH-PAS)超家族转录因子成员。编码的蛋白质作为bHLH-PAS家族的几个传感器蛋白质的伙伴,与响应发育和环境刺激的基因中的调节DNA序列结合。在低氧条件下,编码的蛋白质在细胞核中与低氧诱导因子1alpha复合,这个复合物结合增强子和氧气响应基因启动子中的低氧响应元素。小鼠中高度相似的蛋白质既能与芳香烃受体结合,又能与Single-minded蛋白质形成功能复合物,提示编码蛋白质在代谢外源性化合物和调节神经发生方面分别有其他作用。[由RefSeq提供,2013年12月]
Related ID:
NCBI:9915
ENSEMBL:ENSG00000172379
HGNC:16876
UNIPROT:Q9HBZ2
OMIM:606036
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
9915
1
19
193552 bp
78.69
166
2
6
9
ARNT2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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Name
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Status
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References Literature
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