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中文人类
CDC6 - Cell Division Cycle 6
Alias:
CDC18L
HsCDC6
MGORS5
HsCDC18
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这个基因编码的蛋白质与酿酒酵母Cdc6蛋白高度相似，Cdc6蛋白是DNA复制起始所必需的。这个蛋白质在DNA复制的早期阶段作为调节蛋白发挥作用。在细胞周期的G1期，它定位在细胞核中，但在S期开始时转移到细胞质中。这个蛋白质在细胞周期的亚细胞迁移是通过其被Cdks磷酸化来调节的。据报道，这个蛋白质的转录是通过涉及E2F蛋白的转录调控机制响应有丝分裂信号而调节的。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CDC6 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
