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中文人类
GAB2 - GRB2 Associated Binding Protein 2
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这个基因是GRB2相关结合蛋白（GAB）基因家族的成员。这些蛋白质含有pleckstrin同源性（PH）结构域，并与SHP2酪氨酸磷酸酶和GRB2适配器蛋白结合。它们作为适配器，通过细胞因子和生长因子受体以及T和B细胞抗原受体传递对刺激作出反应的各种信号。这个基因编码的蛋白质是高亲和力IgE受激活后磷脂酰肌醇-3激酶的主要激活物。已在这个基因中描述了两个可选择的剪接转录本，编码不同的异构体。[由RefSeq，2009年11月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
GAB2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
